Daniel J. Drucker

For other people called Daniel Drucker, see Daniel Drucker (disambiguation).
Daniel Drucker

Daniel Drucker in 2015, portrait from the Royal Society
Born Daniel Joshua Drucker
(1956-06-23) June 23, 1956[1]
Montreal, Quebec[1]
Fields
Institutions
Alma mater University of Toronto (MD)[5]
Notable awards

Website

Daniel Joshua Drucker (born 1956)[1] FRS[6] FRCPC MD[5] is a professor of medicine at the Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto.[2][3][7][8][9][10][11] In 1996, Drucker first identified the proliferative effects that GLP-2 has on small bowel proliferation in rats.

Education and career

Drucker graduated in medicine from the University of Toronto (1980), and received postgraduate training (medicine and endocrinology) at Johns Hopkins Hospital (1980–81), the University of Toronto (1980–84) and the Massachusetts General Hospital and Harvard Medical School (1984–87).[12]

Awards and honours

Drucker was elected a Fellow of the Royal Society (FRS) in 2015.[12] His certificate of election reads:

“ Daniel Drucker is renowned for his pioneering studies of gut hormone action enabling development of three new classes of medications for treatment of diabetes and short bowel syndrome (SBS). He demonstrated that GLP-1 stimulates insulin secretion, cloned cDNAs for GLP-1 and exendin-4, and generated Glp1r-/- mice, identifying multiple new cardiometabolic actions of GLP-1. He demonstrated that Dpp4 was essential for glucose homeostasis and identified GIP and GLP-1 as the key substrates transducing glucoregulatory actions of DPP-4 inhibitors. He discovered the first actions of GLP-2, characterized GLP-2 metabolism, and developed teduglutide, the first GLP-2 analogue approved for treatment of SBS.[6] ”

Drucker has received numerous other national and international awards in recognition of his research accomplishments elucidating the mechanisms of action and therapeutic potential of enteroendocrine hormones. These include the Prix Galien Canada for outstanding academic research (2008), the Donald F. Steiner Award for Outstanding Diabetes Research from the University of Chicago (2007), the Clinical Investigator Award from the Endocrine Society (2009), the Claude Bernard Prize from the European Association for the Study of Diabetes (2012), the Oon International Award and Lecture from the University of Cambridge (2014), the Banting Medal for Scientific Achievement from the American Diabetes Association (2014) and the Manpei Suzuki Foundation International Prize for Diabetes (2014). Drucker was named an Officer of the Order of Canada in 2015.[13]

References

  1. 1 2 3 DRUCKER, Prof. Daniel Joshua. Who's Who. 2016 (online Oxford University Press ed.). A & C Black, an imprint of Bloomsbury Publishing plc. (subscription required)
  2. 1 2 Drucker, D. J.; Buse, J. B.; Taylor, K.; Kendall, D. M.; Trautmann, M.; Zhuang, D.; Porter, L. (2008). "Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: A randomised, open-label, non-inferiority study". The Lancet. 372 (9645): 1240–1250. doi:10.1016/S0140-6736(08)61206-4. PMID 18782641.
  3. 1 2 Daniel J. Drucker's publications indexed by Google Scholar
  4. ↑ "Dr. Daniel J. Drucker". MyThyroid.com.
  5. 1 2 "Daniel J. Drucker M.D, FRCPC, Clinical Advisor, Diartis Pharmaceuticals, Inc.". Bloomberg L.P.
  6. 1 2 3 "Professor Daniel Drucker FRS". London: The Royal Society. Archived from the original on 2015-05-02.
  7. ↑ Daniel J. Drucker on Twitter
  8. ↑ Drucker, D. J.; Nauck, M. A. (2006). "The incretin system: Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes". The Lancet. 368 (9548): 1696–705. doi:10.1016/S0140-6736(06)69705-5. PMID 17098089.
  9. ↑ Baggio, L. L.; Drucker, D. J. (2007). "Biology of Incretins: GLP-1 and GIP". Gastroenterology. 132 (6): 2131–57. doi:10.1053/j.gastro.2007.03.054. PMID 17498508.
  10. ↑ Drucker, D. J. (2006). "The biology of incretin hormones". Cell Metabolism. 3 (3): 153–65. doi:10.1016/j.cmet.2006.01.004. PMID 16517403.
  11. ↑ Drucker, D. J.; Philippe, J; Mojsov, S; Chick, W. L.; Habener, J. F. (1987). "Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line". Proceedings of the National Academy of Sciences of the United States of America. 84 (10): 3434–8. doi:10.1073/pnas.84.10.3434. PMC 304885Freely accessible. PMID 3033647.
  12. 1 2 "Professor Daniel Drucker FRS". London: Royal Society. Archived from the original on 2015-11-17. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
    “All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --Royal Society Terms, conditions and policies at the Wayback Machine (archived September 25, 2015)
  13. ↑ "Four Nova Scotians among Order of Canada honourees". The Chronicle-Herald, July 1, 2015.


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