Allan Balmain

Allan Balmain

Allan Balmain in 2015, portrait via the Royal Society
Fields
Institutions
Alma mater University of Glasgow (BSc, PhD)
Thesis Studies in the diterpenoid field (1969)
Notable awards

Website

Allan Balmain FRS[6] is Barbara Bass Bakar Distinguished Professor of Cancer Genetics[5] at the University of California, San Francisco (UCSF).[7][8][9][10][11]

Education

Balmain was educated at the University of Glasgow where he was awarded a Bachelor of Science degree in chemistry in 1966, followed by a PhD on the organic chemistry of terpenoids in 1969.[5]

Awards and honours

Balmain was elected a Fellow of the Royal Society (FRS) in 2015. His certificate of election reads:

“ Allan Balmain has pioneered the use of the mouse as a model system for understanding the complexity of cancer at a genetic, molecular and cellular level. Through his novel and creative experiments he established the first molecular link between cancer initiation and carcinogen exposure, identified how specific genetic events lead to malignant progression and made major advances in our understanding of cancer susceptibility. Balmain’s wide-ranging, innovative use of mouse genetics has generated new approaches for visualizing the genetic architecture of cancer pathways and the roles of complex network interactions in determining an individual’s cancer susceptibility.[6] ”

Balmain was also elected a Fellow of the Royal Society of Edinburgh (FRSE) in 1995.[5]

References

  1. ↑ Balmain, A; Gray, J; Ponder, B (2003). "The genetics and genomics of cancer". Nature Genetics. 33 Suppl (3s): 238–44. doi:10.1038/ng1107. PMID 12610533.
  2. ↑ Quigley, D. A.; To, M. D.; Kim, I. J.; Lin, K. K.; Albertson, D. G.; Sjolund, J.; Pérez-Losada, J. S.; Balmain, A. (2011). "Network analysis of skin tumor progression identifies a rewired genetic architecture affecting inflammation and tumor susceptibility". Genome Biology. 12: R5. doi:10.1186/gb-2011-12-1-r5.
  3. ↑ Cui, W.; Fowlis, D. J.; Bryson, S.; Duffie, E.; Ireland, H.; Balmain, A.; Akhurst, R. J. (1996). "TGFβ1 Inhibits the Formation of Benign Skin Tumors, but Enhances Progression to Invasive Spindle Carcinomas in Transgenic Mice". Cell. 86 (4): 531–542. doi:10.1016/S0092-8674(00)80127-0.
  4. ↑ Merritt, A. J.; Potten, C. S.; Kemp, C. J.; Hickman, J. A.; Balmain, A; Lane, D. P.; Hall, P. A. (1994). "The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice". Cancer Research. 54 (3): 614–7. PMID 8306319.
  5. 1 2 3 4 5 "Allan Balmain, PhD, FRSE". University of California, San Franscisco. Archived from the original on 2013-02-06.
  6. 1 2 3 "Professor Allan Balmain FRS". London: The Royal Society. Archived from the original on 2015-05-02.
  7. ↑ Derynck, R; Akhurst, R. J.; Balmain, A (2001). "TGF-beta signaling in tumor suppression and cancer progression". Nature Genetics. 29 (2): 117–29. doi:10.1038/ng1001-117. PMID 11586292.
  8. ↑ Quintanilla, M; Brown, K; Ramsden, M; Balmain, A (1986). "Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis". Nature. 322 (6074): 78–80. doi:10.1038/322078a0. PMID 3014349.
  9. ↑ Allan Balmain's publications indexed by the Scopus bibliographic database, a service provided by Elsevier. (subscription required)
  10. ↑ Balmain, A.; Barrett, J. C.; Moses, H.; Renan, M. J. (1993). "How many mutations are required for tumorigenesis? Implications from human cancer data". Molecular Carcinogenesis. 7 (3): 139–146. doi:10.1002/mc.2940070303.
  11. ↑ Balmain, A.; Ramsden, M.; Bowden, G. T.; Smith, J. (1984). "Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas". Nature. 307 (5952): 658–660. doi:10.1038/307658a0.
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