Chanoclavine
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| Names | |
|---|---|
| IUPAC name
(E)-2-methyl-3-[(4R,5R)-4-(methylamino)-1,3,4,5-tetrahydrobenzo[cd]indol-5-yl]prop-2-en-1-ol | |
| Other names
chanoclavin-l | |
| Identifiers | |
| 2390-99-0 | |
| 3D model (Jmol) | Interactive image |
| ChemSpider | 4444739 |
| PubChem | 5281381 |
| |
| |
| Properties | |
| C16H20N2O | |
| Molar mass | 256.34 g/mol |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Chanoclavine, also known as chanoclavin-l is a tri-cyclic ergot alkaloid (ergoline) isolate of certain fungi. It is mainly produced by members of the genus claviceps.[1] Long used in traditional Chinese medicine, it was found in 1987 mouse studies to stimulate dopamine D-2 receptors in the brain.[2]
See also
References
- ↑ Lorenz, N; Haarmann, T; Pazoutová, S; Jung, M; Tudzynski, P (2009). "The ergot alkaloid gene cluster: Functional analyses and evolutionary aspects". Phytochemistry. 70 (15–16): 1822–32. doi:10.1016/j.phytochem.2009.05.023. PMID 19695648.
- ↑ Watanabe, H; Somei, M; Sekihara, S; Nakagawa, K; Yamada, F (1987). "Dopamine receptor stimulating effects of chanoclavine analogues, tricyclic ergot alkaloids, in the brain". Japanese journal of pharmacology. 45 (4): 501–6. doi:10.1254/jjp.45.501. PMID 3127619.
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