ZFX

This article is about the protein. For the flying effects company, see ZFX Inc.

ZFX

Identifiers

ZFX, ZNF926, zinc finger protein, X-linked

External IDs

MGI: 99211 HomoloGene: 2561 GeneCards: ZFX

Gene ontology
Molecular function	• transcription factor activity, sequence-specific DNA binding • DNA binding • transcription coactivator activity • RNA polymerase II regulatory region sequence-specific DNA binding • metal ion binding • nucleic acid binding
Cellular component	• nucleus
Biological process	• multicellular organism development • regulation of transcription, DNA-templated • transcription, DNA-templated
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


7543


22764

Ensembl


ENSG00000005889


ENSMUSG00000079509

UniProt


P17010


P17012

RefSeq (mRNA)


NM_001178084 NM_001178085 NM_001178086 NM_001178095 NM_003410


NM_001044386 NM_011768

RefSeq (protein)


NP_001171555.1 NP_001171556.1 NP_001171557.1 NP_003401.2


NP_001037851.1 NP_035898.2

Location (UCSC)

Chr X: 24.15 – 24.22 Mb

Chr X: 94.07 – 94.12 Mb

PubMed search

^[1]

^[2]

Wikidata

View/Edit Human

View/Edit Mouse

Zinc finger X-chromosomal protein is a protein that in humans is encoded by the ZFX gene.^[3]

References

North M, Sargent C, O'Brien J, et al. (1991). "Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY.". Nucleic Acids Res. 19 (10): 2579–86. doi:10.1093/nar/19.10.2579. PMC 328173. PMID 2041734.
Mardon G, Luoh SW, Simpson EM, et al. (1990). "Mouse Zfx protein is similar to Zfy-2: each contains an acidic activating domain and 13 zinc fingers.". Mol. Cell. Biol. 10 (2): 681–8. PMC 360866. PMID 2105457.
Palmer MS, Berta P, Sinclair AH, et al. (1990). "Comparison of human ZFY and ZFX transcripts.". Proc. Natl. Acad. Sci. U.S.A. 87 (5): 1681–5. doi:10.1073/pnas.87.5.1681. PMC 53546. PMID 2308929.
Müller G, Schempp W (1989). "Mapping the human ZFX locus to Xp21.3 by in situ hybridization.". Hum. Genet. 82 (1): 82–4. doi:10.1007/BF00288279. PMID 2497060.
Schneider-Gädicke A, Beer-Romero P, Brown LG, et al. (1989). "ZFX has a gene structure similar to ZFY, the putative human sex determinant, and escapes X inactivation.". Cell. 57 (7): 1247–58. doi:10.1016/0092-8674(89)90061-5. PMID 2500252.
Schneider-Gädicke A, Beer-Romero P, Brown LG, et al. (1990). "Putative transcription activator with alternative isoforms encoded by human ZFX gene.". Nature. 342 (6250): 708–11. doi:10.1038/342708a0. PMID 2512506.
Taylor DM, Ray PF, Ao A, et al. (1998). "Paternal transcripts for glucose-6-phosphate dehydrogenase and adenosine deaminase are first detectable in the human preimplantation embryo at the three- to four-cell stage.". Mol. Reprod. Dev. 48 (4): 442–8. doi:10.1002/(SICI)1098-2795(199712)48:4<442::AID-MRD4>3.0.CO;2-Q. PMID 9364438.
Murphy WJ, Eizirik E, Johnson WE, et al. (2001). "Molecular phylogenetics and the origins of placental mammals.". Nature. 409 (6820): 614–8. doi:10.1038/35054550. PMID 11214319.
Agate RJ, Choe M, Arnold AP (2004). "Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.". Mol. Biol. Evol. 21 (2): 384–96. doi:10.1093/molbev/msh027. PMID 14660691.
Poloumienko A (2004). "Cloning and comparative analysis of the bovine, porcine, and equine sex chromosome genes ZFX and ZFY.". Genome. 47 (1): 74–83. doi:10.1139/g03-099. PMID 15060604.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.

PDB gallery

5znf: ALTERNATING ZINC FINGERS IN THE HUMAN MALE ASSOCIATED PROTEIN ZFY: 2D NMR STRUCTURE OF AN EVEN FINGER AND IMPLICATIONS FOR ""JUMPING-LINKER"" DNA RECOGNITION

This article is issued from Wikipedia - version of the 6/4/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.

ZFX

References

Further reading