WPB
WPB may refer to:
- Welsh Pit Bikes
- War Production Board
- War Propaganda Bureau
- Weekly Playboy
- Weibel–Palade body
- West Palm Beach, Florida
- Workers Party of Bangladesh
- Workers Party of Belgium
- World Painted Blood, a 2009 album by the thrash metal band Slayer
- Waste paper basket
- The hull classification symbol of a USCG Patrol Boat
- White People Balling
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