WDR8

WRAP73
Identifiers
Aliases WRAP73, WDR8, WD repeat containing, antisense to TP73
External IDs MGI: 1891749 HomoloGene: 9857 GeneCards: WRAP73
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

49856

59002

Ensembl

ENSG00000116213

ENSMUSG00000029029

UniProt

Q9P2S5

Q9JM98

RefSeq (mRNA)

NM_017818

NM_021499

RefSeq (protein)

NP_060288.3

NP_067474.2

Location (UCSC) Chr 1: 3.63 – 3.65 Mb Chr 4: 154.14 – 154.17 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

WD repeat-containing protein 8 is a protein that in humans is encoded by the WDR8 gene.[3]

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This family member is 89% identical to the mouse Wdr8 protein at the amino acid level. The function of this protein is not known, and the mouse studies suggest that the Wdr8 protein may play a role in the process of ossification.[3]

References

Further reading


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