W. Mark Saltzman

W. Mark Saltzman
Born (1959-09-08) September 8, 1959
United States
Residence New Haven, Connecticut, United States
Nationality American
Fields Biomedical Engineering
Institutions Johns Hopkins
Cornell University
Yale University
Alma mater Iowa State University
Massachusetts Institute of Technology
Doctoral advisor Robert S. Langer

William Mark Saltzman was named the Goizueta Foundation Professor of Biomedical and Chemical Engineering at Yale University on July 1, 2002 and became the founding chair of Yale’s Department of Biomedical Engineering in 2003.[1] Saltzman’s research aims to promote new methods for drug delivery and develop new biotechnologies to combat human disease. A pioneer in the fields of biomaterials, nanobiotechnology, and tissue engineering, Saltzman has contributed to the design and implementation of a number of clinical technologies that have become essential to medical practice today.[2] His popular course Frontiers of Biomedical Engineering is available to everyone through Open Yale Courses.

Biography

Saltzman received a B.S. in Chemical Engineering in 1981 from Iowa State University, followed by a M.S. in Chemical Engineering in 1984 and a Ph.D. in Medical Engineering in 1987, both at the Massachusetts Institute of Technology.[3]

As a graduate student at the Massachusetts Institute of Technology (MIT), Saltzman built scaffolds that could be seeded with cells to sculpt new replacement tissues. He also created drug-impregnated implants from polymers that slowly and steadily release medicines for long periods—work that now helps patients in the form of GLIADEL, a chemotherapy-loaded polymer wafer that neurosurgeons implant in the brain to combat glioblastoma multiforme (GBM), one of the most aggressive types of malignant brain tumors.[4]

Discovering the Gliadel Wafer

He was appointed Assistant Professor of Chemical Engineering at The Johns Hopkins University in 1987 and received a joint appointment in the Department of Biomedical Engineering at The Johns Hopkins School of Medicine in 1990. He was promoted to Associate Professor in 1992 and to Professor in 1995. In 1996, he moved to Cornell University, holding the first BP Amoco/H. Laurance Fuller Chair in Chemical Engineering.

He joined the faculty at Yale University, as the Goizueta Foundation Professor of Chemical and Biomedical Engineering, in July 2002 and became the first chair of Yale's Department of Biomedical Engineering in 2003. Since he arrived at Yale in 2002 to form the new department, he has seen his faculty group grow to 19 members. He hired slowly, knowing that each new person would have a significant effect on the overall department culture. Saltzman settled on four areas to excel in: imaging, biomolecular engineering, biomechanics, and systems biology. The department has developed largely as its founders envisioned—multidisciplinary, collegial, integrated with the medical school, and committed to undergraduate education.[5]

As of July 1, 2016, Saltzman will serve as Head of Jonathan Edwards College at Yale University.[6]

Research

Saltzman's research focuses on developing the most economical, transportable and accessible methods for disease prevention and methods to more effectively deliver chemotherapy to the most aggressive forms of brain tumors. Dr. Saltzman’s research interests include controlled drug delivery to the brain, polymers for supplementing or stimulating the immune system, cell interactions with polymers, and tissue engineering. He studies how to create safer and more effective medical and surgical therapy based on tissue engineering. Dr. Saltzman worked with an interdisciplinary team to develop what is now the standard of care for treating brain tumors.[7][8]

Awards and honors

Committed to Undergraduate Teaching

Works

Books

Selected Publications

SEM image of nanoparticles

References

  1. ↑ "W. Mark Saltzman of Yale Announced as 2014 Mines Medalist". PRWEB.
  2. ↑ "Chair of biomedical engineering joins Institute of Medicine".
  3. ↑ Yale University faculty page
  4. ↑ "Chair of biomedical engineering joins Institute of Medicine".
  5. ↑ Hoffman, Christopher. "Human body as machine: How Yale launched the Department of Biomedical Engineering".
  6. ↑ http://news.yale.edu/2016/05/06/next-head-jonathan-edwards-college-be-w-mark-saltzman
  7. ↑ W. Mark Saltzman1 & William L. Olbricht "Building drug delivery into tissue engineering design" Nature Reviews Drug Discovery 1, 177-186 (March 2002) | doi:10.1038/nrd744
  8. ↑ Yale University Biological and Biomedical Sciences Faculty http://bbs.yale.edu/people/mark_saltzman-2.profile. Missing or empty |title= (help)
  9. ↑ "Yale Official Web Page".

Yale School of Engineering & Applied Science faculty

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