Vitamin D and Omega-3 Trial
Vitamin D and Omega-3 Trial (VITAL) (VITamin D and OmegA-3 TriaL) is a 5 year trial to run from 2010 to determine the benefits of vitamin D and Omega-3 supplements on elderly Americans.[1] [2]
It aims to enroll 20,000 participants (women 55 or over, men 50 or over)[3][4] who will be randomized to one of four groups:[2]
- daily vitamin D (2000 IU) and fish oil (1 g);
- daily vitamin D and fish-oil placebo;
- daily vitamin-D placebo and fish oil;
- daily vitamin-D placebo and fish-oil placebo.
Participants will answer annual questionnaires[2] to determine effects on risk of cancer, heart disease, stroke, osteoporosis, diabetes, memory loss and depression.
References
- ↑ "Massive Vitamin-D/Omega-3 Trial for CVD, Cancer Prevention"
- 1 2 3 VITAL Study
- ↑ Manson, JE.; Bassuk, SS.; Lee, IM.; Cook, NR.; Albert, MA.; Gordon, D.; Zaharris, E.; Macfadyen, JG.; et al. (Jan 2012). "The VITamin D and OmegA-3 TriaL (VITAL): rationale and design of a large randomized controlled trial of vitamin D and marine omega-3 fatty acid supplements for the primary prevention of cancer and cardiovascular disease". Contemp Clin Trials. 33 (1): 159–71. doi:10.1016/j.cct.2011.09.009. PMC 3253961
. PMID 21986389. - ↑ http://www.vitalstudy.org/QA.html#eligible Retrieved April 5, 2013
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