Diagnosis: Murder (season 6)

Caitlin Sweeney bombed Community General in the last episode, and a number of characters are trapped in the rubble. Mark worked hard to save Amanda's life. After 4 months pass, the hospital starts to reopen, and Steve announces that Caitlin has started robbing banks to raise money for ROR: The Revolutionary Movement Against the US Shadow Government. Steve and Jesse discuss plans to buy Barbecue Bob's, which is going out of business.

With help from the groom, a bride plots the murder of her father, planning to frame her stepmother for the crime.

A supposedly dead man escapes from the pathology lab and terrorizes Community General.

A mystery novelist murders her agent, hoping the investigation will inspire her next book. Guest Stars: Shelley Long, Adam West and Richard Herd

After Amanda reports seeing a murder on the Internet, a hacker messes up all her online transactions. Three hacker friends of Jesse fight back, using The Weasel. Hence ensues the battle of the hackers.

Steve joins his troubled partner, Reggie Ackroyd (Joe Penny) in a rehab facility for stressed-out cops. Reggie seems delusional and keeps blaming a murderer he caught for abducting his wife and daughter, and Steve encourages him. He and Steve are released and go hunting for them, and find their bodies by following the voices in Reggie's head. But Diagnosis Murder has not gone superstitious; there is a perfectly rational explanation at the end.

Jesse and Susan get stuck in a small coastal town with car trouble, on their way to Carmel for a romantic getaway. Susan spots her fiancė, Greg (Laurence Lau), who supposedly died 5 years ago. The town seems very affluent without any apparent source of wealth. Greg is murdered, and Jessie and Susan are charged with the crime by Sheriff Kelso (Monte Markham), in an attempt to cover up the town's dirty secret.

Steve goes undercover to investigate a series of murders at an exclusive gated community.

A retiring detective Harry Trumble (Jack Klugman) continues to pursue a murderer known as "The Clown Killer", and will lie, cheat and kill to do it.

An accident victim develops a fatal attraction to Jesse.

A heavily armed criminal seems to have a death wish.

A juvenile delinquent, Tommy Anders (Shane Van Dyke), is assigned community-service time at a boxing gym, where the death of a young fighter arouses suspicion. He ran in front of a bus to show that he was invincible. (If some of the other delinquents at the gym resemble Tommy, it's no accident, because there are other Van Dyke kids there.) Something in the bottled drinks is making the young boxers very pugnacious. (If some of the other delinquents at the gym resemble Tommy, it's no accident, because there are other Van Dyke kids there.)

A masked magician is murdered during a live television special that reveals the secrets behind his illusions – and the killing could have been a ratings stunt. When the murderer is caught, a new case begins in the death of an actor who was fatally shot during the filming of a TV series based on Sloan's life.

Mark Sloan attempts to have a new doctor arrested for murder after she helps a pair of terminally ill patients commit suicide. Guest Star: Kim Little (plays Nurse Susan Hilliard), and Arthur Rosenberg (plays Harold Lomax, in his first appearance he is played by Richard Fancy and is the Administrator at Community General Hospital).