SRPX2
SRPX2 | ||||||
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Identifiers | ||||||
Aliases | SRPX2, BPP, CBPS, PMGX, RESDX, SRPUL, sushi repeat containing protein, X-linked 2 | |||||
External IDs | MGI: 1916042 HomoloGene: 8704 GeneCards: SRPX2 | |||||
RNA expression pattern | ||||||
More reference expression data | ||||||
Orthologs | ||||||
Species | Human | Mouse | ||||
Entrez | ||||||
Ensembl | ||||||
UniProt | ||||||
RefSeq (mRNA) | ||||||
RefSeq (protein) | ||||||
Location (UCSC) | Chr X: 100.64 – 100.67 Mb | Chr X: 133.91 – 133.93 Mb | ||||
PubMed search | [1] | [2] | ||||
Wikidata |
View/Edit Human | View/Edit Mouse |
Sushi repeat-containing protein SRPX2 is a protein that in humans is encoded by the SRPX2 gene.[3][4] Bioinformatics analysis suggests the SRPX2 protein is a peroxiredoxin.[5]
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ Kurosawa H, Goi K, Inukai T, Inaba T, Chang KS, Shinjyo T, Rakestraw KM, Naeve CW, Look AT (January 1999). "Two candidate downstream target genes for E2A-HLF". Blood. 93 (1): 321–32. PMID 9864177.
- ↑ "Entrez Gene: SRPX2 sushi-repeat-containing protein, X-linked 2".
- ↑ Pawłowski K, Muszewska A, Lenart A, Szczepińska T, Godzik A, Grynberg M (2010). "A widespread peroxiredoxin-like domain present in tumor suppression- and progression-implicated proteins". BMC Genomics. 11: 590. doi:10.1186/1471-2164-11-590. PMC 3091736. PMID 20964819.
Further reading
- Suzuki Y, Taira H, Tsunoda T, Mizushima-Sugano J, Sese J, Hata H, Ota T, Isogai T, Tanaka T, Morishita S, Okubo K, Sakaki Y, Nakamura Y, Suyama A, Sugano S (May 2001). "Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites". EMBO Reports. 2 (5): 388–93. doi:10.1093/embo-reports/kve085. PMC 1083880. PMID 11375929.
- Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S (September 2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Research. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
- Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, Wakamatsu A, Kimura K, Sakamoto K, Hatano N, Kawai Y, Ishii S, Saito K, Kojima S, Sugiyama T, Ono T, Okano K, Yoshikawa Y, Aotsuka S, Sasaki N, Hattori A, Okumura K, Nagai K, Sugano S, Isogai T (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Research. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
- Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Roll P, Rudolf G, Pereira S, Royer B, Scheffer IE, Massacrier A, Valenti MP, Roeckel-Trevisiol N, Jamali S, Beclin C, Seegmuller C, Metz-Lutz MN, Lemainque A, Delepine M, Caloustian C, de Saint Martin A, Bruneau N, Depétris D, Mattéi MG, Flori E, Robaglia-Schlupp A, Lévy N, Neubauer BA, Ravid R, Marescaux C, Berkovic SF, Hirsch E, Lathrop M, Cau P, Szepetowski P (April 2006). "SRPX2 mutations in disorders of language cortex and cognition". Human Molecular Genetics. 15 (7): 1195–207. doi:10.1093/hmg/ddl035. PMID 16497722.
- Royer B, Soares DC, Barlow PN, Bontrop RE, Roll P, Robaglia-Schlupp A, Blancher A, Levasseur A, Cau P, Pontarotti P, Szepetowski P (2008). "Molecular evolution of the human SRPX2 gene that causes brain disorders of the Rolandic and Sylvian speech areas". BMC Genetics. 8: 72. doi:10.1186/1471-2156-8-72. PMC 2151080. PMID 17942002.
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