SORBS3

SORBS3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases SORBS3, SCAM-1, SCAM1, SH3D4, sorbin and SH3 domain containing 3
External IDs MGI: 700013 HomoloGene: 4218 GeneCards: SORBS3
Genetically Related Diseases
human immunodeficiency virus infectious disease[1]
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

10174

20410

Ensembl

ENSG00000120896

ENSMUSG00000022091

UniProt

O60504

Q9R1Z8

RefSeq (mRNA)

NM_001018003
NM_005775

NM_001271407
NM_001271408
NM_001271409
NM_011366

RefSeq (protein)

NP_001018003.1
NP_005766.3

NP_035496.1

Location (UCSC) Chr 8: 22.54 – 22.58 Mb Chr 14: 70.18 – 70.21 Mb
PubMed search [2] [3]
Wikidata
View/Edit HumanView/Edit Mouse

Vinexin is a protein that in humans is encoded by the SORBS3 gene.[4][5][6]

Interactions

SORBS3 has been shown to interact with DLG5[7] and MAPK1.[8]

References

  1. "Diseases that are genetically associated with SORBS3 view/edit references on wikidata".
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. Kioka N; Sakata S; Kawauchi T; Amachi T; Akiyama SK; Okazaki K; Yaen C; Yamada KM; Aota S (Mar 1999). "Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization". J Cell Biol. 144 (1): 59–69. doi:10.1083/jcb.144.1.59. PMC 2148117Freely accessible. PMID 9885244.
  5. Kioka N (Jan 2003). "[A novel adaptor protein family regulating cytoskeletal organization and signal transduction--Vinexin, CAP/ponsin, ArgBP2]". Seikagaku. 74 (11): 1356–60. PMID 12510380.
  6. "Entrez Gene: SORBS3 sorbin and SH3 domain containing 3".
  7. Wakabayashi, Makoto; Ito Takuya; Mitsushima Masaru; Aizawa Sanae; Ueda Kazumitsu; Amachi Teruo; Kioka Noriyuki (Jun 2003). "Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell-cell contact". J. Biol. Chem. United States. 278 (24): 21709–14. doi:10.1074/jbc.M211004200. ISSN 0021-9258. PMID 12657639.
  8. Mitsushima, Masaru; Suwa Akira; Amachi Teruo; Ueda Kazumitsu; Kioka Noriyuki (Aug 2004). "Extracellular signal-regulated kinase activated by epidermal growth factor and cell adhesion interacts with and phosphorylates vinexin". J. Biol. Chem. United States. 279 (33): 34570–7. doi:10.1074/jbc.M402304200. ISSN 0021-9258. PMID 15184391.

Further reading


This article is issued from Wikipedia - version of the 6/5/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.