Rescue fusion hybridization

Rescue fusion hybridization is a process used to manufacture some therapeutic cancer vaccines in which individual tumor cells obtained through biopsy are fused with an antibody-secreting cell to form a heterohybridoma. This cell then secretes the unique idiotype, or immunoglobulin antigen characteristic of the individual tumor, which is purified for use as the vaccine.[1]

It is used to produce the BiovaxID vaccine for follicular lymphoma.

References


This article is issued from Wikipedia - version of the 10/21/2010. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.