Reinke crystals

Reinke crystals are rod-like cytoplasmic inclusions which can be found in Leydig cells of the testes.[1] Occurring only in adult humans and wild bush rats, their function is unknown. [2]

They are large enough to be seen in an optical microscope and can be visualized using Giemsa, trichrome, Gram, and PAS stains.[3] Reinke crystals are rare in normal testes, but are found in approximately 1/3 of all Leydig cell tumours.[4]

These crystals are named after the German anatomist Friedrich Berthold Reinke.[5]

References

  1. ↑ Young, Barbara; Woodford, Phillip; O'Dowd, Geraldine (2013-10-09). Wheater's Functional Histology: A Text and Colour Atlas (FUNCTIONAL HISTOLOGY (WHEATER'S)) (Kindle Locations 9938-9939). Elsevier Health Sciences UK. Kindle Edition.
  2. ↑ Young, Barbara; Woodford, Phillip; O'Dowd, Geraldine. Wheater's Functional Histology: A Text and Colour Atlas (2014), Sixth Edition, Elsevier, Philadelphia, p. 344.
  3. ↑ Mesa Hector, Gilles Scott, Smith Sophia, Dachel Susan, Larson Wendy, Manivel J. Carlos, The Mystery of the Vanishing Reinke Crystals, Human Pathology (2015), doi: 10.1016/j.humpath.2015.01.004
  4. ↑ T. M. Ulbright and R. H. Young. AFIP Atlas of tumour pathology. Tumours of the testis and adjacent structures. Fourth series fascicle 18, Silver Spring, Maryland: ARP Press, 2013, p. 271–286.
  5. ↑ "Friedrich Berthold Reinke". Whonamedit.com. Retrieved 12 February 2015.
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