Psychotropic alkylamines

Psychotropic alkylamines are alkylamines that share the critical property of not containing an aromatic nucleus, but are still biologically active. While many of these molecules are stimulants (some of them natural), others are antiviral, have competitive NMDA antagonist activity, or are nicotinic receptor antagonists.

Compound Core OtherN Substituent Pharmacology
Neramexane Cyclohexyl1,3,3,5,5-Pentamethyl 1-NH2 NMDA antagonist
Amantadineadamantane1-NH2antiviral, NMDA antagonist, catecholamine releaser, cholinergic
Memantine"3,5-DiMe"NMDA antagonist
Rimantadine"CH3CHNH2antiviral
Cyclopentaminecyclopentanen-propyl2-NHMeSympathomimetic vasoconstrictor
Propylhexedrinecyclohexane"""
Methylhexanaminen-hexane4-methyl2-NH2"
Tuaminoheptanen-heptane2-NH2"
Octodrine"6-methyl""
Mecamylaminenorbornane1-exo-2,2-trimethyl1-endo-NHMenicotinic antagonist

Alkenylamines

Isometheptene

Alkanolamines

Heptaminol


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