Protein-methionine-S-oxide reductase
| Protein-methionine-S-oxide reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.8.4.6 | ||||||||
| CAS number | 78206-57-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Protein-methionine-S-oxide reductase (EC 1.8.4.6, methionine sulfoxide (protein) reductase, methionine sulfoxide peptide reductase, protein (methionine sulfoxide) reductase, Met(O)-peptide reductase, peptide methionine sulfoxide reductase, protein-L-methionine:oxidized-thioredoxin S-oxidoreductase) is an enzyme with systematic name protein-L-methionine:thioredoxin-disulfide S-oxidoreductase.[1] This enzyme catalyses the following chemical reaction
- protein L-methionine + thioredoxin disulfide protein L-methionine S-oxide + thioredoxin
Dithiothreitol can replace a reduced thioredoxin in the reverse reaction.
References
- ↑ Brot, N.; Weissbach, L.; Werth, J.; Weissbach, H. (1981). "Enzymatic reduction of protein-bound methionine sulfoxide". Proc. Natl. Acad. Sci. USA. 78 (4): 2155–2158. doi:10.1073/pnas.78.4.2155. PMC 319302
. PMID 7017726.
External links
- Protein-methionine-S-oxide reductase at the US National Library of Medicine Medical Subject Headings (MeSH)
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