Prime Directive (disambiguation)
Prime Directive may refer to:
- Prime Directive, the guiding principle of Star Trek's Starfleet;
- Prime Directive (role-playing game), by the Amarillo Design Bureau;
- Prime Directive (album), an album by the Dave Holland Quintet;
- Prime Directive (Star Trek novel), by Judith and Garfield Reeves-Stevens;
- Prime Directive Records, a record label;
- A fake working title of the Transformers (film series).
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