Orotidine 5'-monophosphate
Names | |
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IUPAC name
3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]-2,6-dioxo-pyrimidine-4-carboxylic acid | |
Other names
Orotidylic acid, OMP | |
Identifiers | |
2149-82-8 | |
3D model (Jmol) | Interactive image |
ChemSpider | 141140 |
MeSH | Orotidine+5'-monophosphate |
PubChem | 160617 |
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Properties | |
C10H13N2O11P | |
Molar mass | 368.191 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
Orotidine 5'-monophosphate (OMP), also known as orotidylic acid, is a pyrimidine nucleotide which is the last intermediate in the biosynthesis of uridine monophosphate. OMP is formed from orotate and phosphoribosyl pyrophosphate by the enzyme Orotate phosphoribosyltransferase
In humans, the enzyme UMP synthase converts OMP into uridine 5'- monophosphate. If UMP synthase is defective, orotic aciduria can result.
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