Neurotrimin

NTM
Identifiers
Aliases NTM, HNT, IGLON2, NTRI, neurotrimin
External IDs MGI: 2446259 HomoloGene: 41139 GeneCards: NTM
Genetically Related Diseases
obesity, Asperger syndrome[1]
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

50863

235106

Ensembl

ENSG00000182667

ENSMUSG00000059974

UniProt

Q9P121

Q99PJ0

RefSeq (mRNA)

NM_001048209
NM_001144058
NM_001144059
NM_016522

NM_172290

RefSeq (protein)

NP_001041674.1
NP_001137530.1
NP_001137531.1
NP_057606.1

n/a

Location (UCSC) Chr 11: 131.37 – 132.34 Mb Chr 9: 28.99 – 29.96 Mb
PubMed search [2] [3]
Wikidata
View/Edit HumanView/Edit Mouse

Neurotrimin is a protein that in humans is encoded by the NTM gene.[4][5]

This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple alternatively spliced variants have been found but only two variants have had their full-length sequences determined.[5]

References

  1. "Diseases that are genetically associated with NTM view/edit references on wikidata".
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. Struyk AF, Canoll PD, Wolfgang MJ, Rosen CL, D'Eustachio P, Salzer JL (Apr 1995). "Cloning of neurotrimin defines a new subfamily of differentially expressed neural cell adhesion molecules". J Neurosci. 15 (3 Pt 2): 2141–56. PMID 7891157.
  5. 1 2 "Entrez Gene: HNT neurotrimin".

Further reading

This article is issued from Wikipedia - version of the 6/17/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.