NRD1

NRDC
Identifiers
Aliases NRDC, hNRD1, hNRD2, NRD1, nardilysin convertase
External IDs MGI: 1201386 HomoloGene: 68260 GeneCards: NRDC
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

4898

230598

Ensembl

ENSG00000078618

ENSMUSG00000053510

UniProt

O43847

Q8BHG1

RefSeq (mRNA)

NM_001101662
NM_001242361
NM_002525

NM_146150

RefSeq (protein)

NP_001095132.1
NP_001229290.1
NP_002516.2

NP_666262.2

Location (UCSC) Chr 1: 51.79 – 51.88 Mb Chr 4: 109 – 109.06 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Nardilysin is a protein that in humans is encoded by the NRD1 gene.[3][4][5]

Interactions

NRD1 has been shown to interact with Heparin-binding EGF-like growth factor.[6]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Hospital V, Prat A, Joulie C, Cherif D, Day R, Cohen P (May 1998). "Human and rat testis express two mRNA species encoding variants of NRD convertase, a metalloendopeptidase of the insulinase family". Biochem J. 327 (3): 773–9. PMC 1218856Freely accessible. PMID 9581555.
  4. Fumagalli P, Accarino M, Egeo A, Scartezzini P, Rappazzo G, Pizzuti A, Avvantaggiato V, Simeone A, Arrigo G, Zuffardi O, Ottolenghi S, Taramelli R (Apr 1998). "Human NRD convertase: a highly conserved metalloendopeptidase expressed at specific sites during development and in adult tissues". Genomics. 47 (2): 238–45. doi:10.1006/geno.1997.5078. PMID 9479496.
  5. "Entrez Gene: NRD1 nardilysin (N-arginine dibasic convertase)".
  6. Nishi, E; Prat A; Hospital V; Elenius K; Klagsbrun M (Jul 2001). "N-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor that mediates cell migration". EMBO J. England. 20 (13): 3342–50. doi:10.1093/emboj/20.13.3342. ISSN 0261-4189. PMC 125525Freely accessible. PMID 11432822.

Further reading


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