Mycobacterial porin
| MspA | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifiers | |||||||||
| Symbol | MspA | ||||||||
| Pfam | PF09203 | ||||||||
| InterPro | IPR015286 | ||||||||
| SCOP | 1uun | ||||||||
| SUPERFAMILY | 1uun | ||||||||
| TCDB | 1.B.24 | ||||||||
| OPM superfamily | 305 | ||||||||
| OPM protein | 1uun | ||||||||
| |||||||||
MspA porin is a membrane porin produced by Mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eightfold rotation symmetry that resembles a goblet and contains a central channel. Each protein subunit contains a beta-sandwich of immunnoglobulin-like topology and a beta-ribbon arm that forms an oligomeric transmembrane beta-barrel.[1]
References
- ↑ Schulz GE, Faller M, Niederweis M (2004). "The structure of a mycobacterial outer-membrane channel". Science. 303 (5661): 1189–92. doi:10.1126/science.1094114. PMID 14976314.
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