MicC RNA

MicC RNA
Predicted secondary structure and sequence conservation of MicC
Identifiers
Symbol MicC
Alt. Symbols IS063
Rfam RF00121
Other data
RNA type Gene; sRNA
Domain(s) Bacteria
SO 0000655

The MicC non-coding RNA (previously known as IS063 [1]) is located between the ompN and ydbK genes in E. coli. This RNA is thought to be a regulator of the expression level of the OmpC porin protein, with a 5' region of 22 nucleotides potentially forming an antisense interaction with the ompC mRNA. Along with MicF RNA this family may act in conjunction with EnvZ-OmpR two-component system to control the OmpF/OmpC protein ratio in response to a variety of environmental stimuli.[2]

See also

References

  1. Chen, S; Lesnik EA; Hall TA; Sampath R; Griffey RH; Ecker DJ; Blyn LB (2002). "A bioinformatics based approach to discover small RNA genes in the Escherichia coli genome". Biosystems. 65 (2–3): 157177. doi:10.1016/S0303-2647(02)00013-8. PMID 12069726.
  2. Chen, S; Zhang A; Blyn LB; Storz G (2004). "MicC, a Second Small-RNA Regulator of Omp Protein Expression in Escherichia coli". J Bacteriol. 186 (20): 66896697. doi:10.1128/JB.186.20.6689-6697.2004. PMC 522180Freely accessible. PMID 15466019.

Further reading

External links


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