MPP2

MPP2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases MPP2, DLG2, membrane palmitoylated protein 2
External IDs MGI: 1858257 HomoloGene: 3920 GeneCards: MPP2
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

4355

50997

Ensembl

ENSG00000108852

ENSMUSG00000017314

UniProt

Q14168

Q9WV34

RefSeq (mRNA)

NM_016695

RefSeq (protein)

NP_057904.1

Location (UCSC) Chr 17: 43.88 – 43.91 Mb Chr 11: 102.06 – 102.09 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

MAGUK p55 subfamily member 2 is a protein that in humans is encoded by the MPP2 gene.[3][4]

Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction.[4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Mazoyer S, Gayther SA, Nagai MA, Smith SA, Dunning A, van Rensburg EJ, Albertsen H, White R, Ponder BA (Dec 1995). "A gene (DLG2) located at 17q12-q21 encodes a new homologue of the Drosophila tumor suppressor dIg-A". Genomics. 28 (1): 25–31. doi:10.1006/geno.1995.1101. PMID 7590743.
  4. 1 2 "Entrez Gene: MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)".

Further reading


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