MOV10

MOV10

Identifiers

MOV10, fSAP113, gb110, Mov10 RISC complex RNA helicase

External IDs

MGI: 97054 HomoloGene: 10365 GeneCards: MOV10

Genetically Related Diseases

hypertension^[1]

Gene ontology
Molecular function	• nucleotide binding • helicase activity • protein binding • RNA binding • poly(A) RNA binding • hydrolase activity • ATP binding
Cellular component	• cytoplasm • cytosol • P-body • extracellular fluid
Biological process	• regulation of transcription, DNA-templated • transcription, DNA-templated • mRNA cleavage involved in gene silencing by miRNA • gene silencing by RNA • phosphatidylinositol-mediated signaling • Wnt signaling pathway, calcium modulating pathway • gene silencing by miRNA
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


4343


17454


ENSG00000155363


ENSMUSG00000002227


Q9HCE1


P23249

RefSeq (mRNA)


NM_001130079 NM_001286072 NM_020963 NM_001321324


NM_001163440 NM_001163441 NM_008619

RefSeq (protein)


NP_001123551.1 NP_001273001.1 NP_066014.1 NP_001308253.1


NP_001156912.1 NP_001156913.1 NP_032645.2

Location (UCSC)

Chr 1: 112.67 – 112.7 Mb

Chr 3: 104.79 – 104.82 Mb

PubMed search

^[2]

^[3]

View/Edit Human

View/Edit Mouse

Putative helicase MOV-10 is an enzyme that in humans is encoded by the MOV10 gene.^[4]

References

Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Nagase T, Kikuno R, Nakayama M, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (4): 273–81. doi:10.1093/dnares/7.4.271. PMID 10997877.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Meister G, Landthaler M, Peters L, et al. (2006). "Identification of novel argonaute-associated proteins". Curr. Biol. 15 (23): 2149–55. doi:10.1016/j.cub.2005.10.048. PMID 16289642.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

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