MED31

MED31
Identifiers
Aliases MED31, 3110004H13Rik, Soh1, CGI-125, mediator complex subunit 31
External IDs MGI: 1914529 HomoloGene: 9368 GeneCards: MED31
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

51003

67279

Ensembl

ENSG00000108590

ENSMUSG00000020801

UniProt

Q9Y3C7

Q9CXU1

RefSeq (mRNA)

NM_016060

NM_026068

RefSeq (protein)

NP_057144.1

NP_080344.2

Location (UCSC) Chr 17: 6.64 – 6.65 Mb Chr 11: 72.21 – 72.22 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse
Med31
Identifiers
Symbol Med31
Pfam PF05669
InterPro IPR008831

Mediator of RNA polymerase II transcription subunit 31 is a protein in humans encoded by the MED31 gene.[3][4] It represents subunit Med31 of the Mediator complex. The family contains the Saccharomyces cerevisiae SOH1 homologues. SOH1 is responsible for the repression of temperature sensitive growth of the HPR1 mutant [5] and has been found to be a component of the RNA polymerase II transcription complex. SOH1 not only interacts with factors involved in DNA repair, but transcription as well. Thus, the SOH1 protein may serve to couple these two processes.[6]

References

Further reading

This article incorporates text from the public domain Pfam and InterPro IPR008831


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