MAP kinase phosphatase
Dual-specificity phosphatases have been recognized as key players for inactivating different map kinase isoforms; this class of phosphatases has been designated MAP Kinase phosphatases[1]
On the basis of structures predicted from genomic sequence, the MKP's can readily be divided into subgroups (Table 1).
Table 1
| DUSP | Sub Group |
|---|---|
| DUSP1 | I |
| DUSP2 | I |
| DUSP4 | I |
| DUSP5 | I |
| DUSP6 | II |
| DUSP7 | II |
| DUSP8 | III |
| DUSP9 | II |
| DUSP10 | ? |
| DUSP16 | III |
Subgroups of Map kinase phosphatase and their subgroups.
References
- ↑ Aspasia Theodosiou and Alan Ashworth, Map Kinase Phosphatases Genome Biology 2002, 3(7):reviews3009.1-3009.10
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