List of immunofluorescence findings for autoimmune bullous conditions
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See also: List of cutaneous conditions
Several cutaneous conditions can be diagnosed with the aid of immunofluorescence studies.
Cutaneous conditions with positive direct or indirect immunofluorescence when using salt-split skin include:
Condition | Antibody isotype(s) deposited | Localization of antibody with use of salt-split skin |
---|---|---|
Antiepilegrin cicatricial pemphigoid | IgG | Dermal |
Bullous lupus erythematosus | Dermal | |
Bullous pemphigoid | IgG | Epidermal |
Cicatricial pemphigoid | IgG | Epidermal |
Epidermolysis bullosa acquisita | IgG | Dermal |
Linear IgA bullous dermatosis | IgA | Epidermal |
Orf-induced immunobullous disease | IgG | Dermal |
Pemphigoid gestationis | IgG | Epidermal |
For several subtypes of pemphigus a variety of substrates are used for indirect immunofluorescence:
Pemphigus variant | Substrate |
---|---|
Pemphigus foliaceous | Guinea pig esophagus |
Pemphigus vulgaris | Monkey esophagus |
IgA pemphigus | Cultured skin |
Paraneoplastic pemphigus | Rat bladder |
See also
- List of cutaneous conditions
- List of genes mutated in cutaneous conditions
- List of cutaneous conditions caused by mutations in keratins
References
- Bolognia, Jean L.; et al. (2007). Dermatology. St. Louis: Mosby. ISBN 1-4160-2999-0.
- James, William D.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
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