KLHDC3

KLHDC3
Identifiers
Aliases KLHDC3, PEAS, dJ20C7.3, kelch domain containing 3
External IDs MGI: 2651568 HomoloGene: 14290 GeneCards: KLHDC3
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

116138

71765

Ensembl

ENSG00000124702

ENSMUSG00000063576

UniProt

Q9BQ90

Q8VEM9

RefSeq (mRNA)

NM_001242872
NM_057161

NM_001163729
NM_027910

RefSeq (protein)

NP_476502.1

NP_001157201.2
NP_082186.2

Location (UCSC) Chr 6: 43.01 – 43.02 Mb Chr 17: 46.67 – 46.68 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Kelch domain-containing protein 3 is a protein that in humans is encoded by the KLHDC3 gene.[3][4]

The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2 (RAG2), a protein involved in the activation of the V(D)J recombination. This gene is found to express specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasm and meiotic chromatin, which suggests that this gene may be involved in meiotic recombination.[4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Ohinata Y, Sutou S, Kondo M, Takahashi T, Mitsui Y (Nov 2002). "Male-enhanced antigen-1 gene flanked by two overlapping genes is expressed in late spermatogenesis". Biol Reprod. 67 (6): 1824–31. doi:10.1095/biolreprod.101.002550. PMID 12444059.
  4. 1 2 "Entrez Gene: KLHDC3 kelch domain containing 3".

Further reading


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