KIF20A
| KIF20A | |||||||||||||||||
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| Identifiers | |||||||||||||||||
| Aliases | KIF20A, MKLP2, RAB6KIFL, kinesin family member 20A | ||||||||||||||||
| External IDs | MGI: 1201682 HomoloGene: 38093 GeneCards: KIF20A | ||||||||||||||||
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| Orthologs | |||||||||||||||||
| Species | Human | Mouse | |||||||||||||||
| Entrez | |||||||||||||||||
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| Location (UCSC) | Chr 5: 138.18 – 138.19 Mb | Chr 18: 34.62 – 34.63 Mb | |||||||||||||||
| PubMed search | [1] | [2] | |||||||||||||||
| Wikidata | |||||||||||||||||
| View/Edit Human | View/Edit Mouse |
Kinesin-like protein KIF20A is a protein that in humans is encoded by the KIF20A gene.[3][4][5]
Interactions
KIF20A has been shown to interact with RAB6A.[6][7]
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ Miki H, Setou M, Kaneshiro K, Hirokawa N (June 2001). "All kinesin superfamily protein, KIF, genes in mouse and human". Proc Natl Acad Sci U S A. 98 (13): 7004–11. doi:10.1073/pnas.111145398. PMC 34614
. PMID 11416179. - ↑ Lai F, Fernald AA, Zhao N, Le Beau MM (July 2000). "cDNA cloning, expression pattern, genomic structure and chromosomal location of RAB6KIFL, a human kinesin-like gene". Gene. 248 (1–2): 117–25. doi:10.1016/S0378-1119(00)00135-9. PMID 10806357.
- ↑ "Entrez Gene: KIF20A kinesin family member 20A".
- ↑ Echard A, Jollivet F, Martinez O, Lacapère JJ, Rousselet A, Janoueix-Lerosey I, Goud B (January 1998). "Interaction of a Golgi-associated kinesin-like protein with Rab6". Science. 279 (5350): 580–5. doi:10.1126/science.279.5350.580. PMID 9438855.
- ↑ Echard A, Opdam FJ, de Leeuw HJ, Jollivet F, Savelkoul P, Hendriks W, Voorberg J, Goud B, Fransen JA (November 2000). "Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms". Mol. Biol. Cell. 11 (11): 3819–33. doi:10.1091/mbc.11.11.3819. PMC 15039. PMID 11071909.
Further reading
- Echard A, Jollivet F, Martinez O, Lacapère JJ, Rousselet A, Janoueix-Lerosey I, Goud B (1998). "Interaction of a Golgi-associated kinesin-like protein with Rab6". Science. 279 (5350): 580–5. doi:10.1126/science.279.5350.580. PMID 9438855.
- Horrevoets AJ, Fontijn RD, van Zonneveld AJ, de Vries CJ, ten Cate JW, Pannekoek H (1999). "Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes". Blood. 93 (10): 3418–31. PMID 10233894.
- Opdam FJ, Echard A, Croes HJ, van den Hurk JA, van de Vorstenbosch RA, Ginsel LA, Goud B, Fransen JA (2000). "The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus". J. Cell. Sci. 113 (15): 2725–35. PMID 10893188.
- Hill E, Clarke M, Barr FA (2000). "The Rab6-binding kinesin, Rab6-KIFL, is required for cytokinesis". EMBO J. 19 (21): 5711–9. doi:10.1093/emboj/19.21.5711. PMC 305783. PMID 11060022.
- Echard A, Opdam FJ, de Leeuw HJ, Jollivet F, Savelkoul P, Hendriks W, Voorberg J, Goud B, Fransen JA (2001). "Alternative Splicing of the Human Rab6A Gene Generates Two Close but Functionally Different Isoforms". Mol. Biol. Cell. 11 (11): 3819–33. doi:10.1091/mbc.11.11.3819. PMC 15039. PMID 11071909.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Nagura M, Nagao Y, Takita J, Igarashi T, LeGuern E, Hayashi Y (2003). "The kinesin superfamily protein Rab6KIFL is not involved in the pathophysiology of Charcot-Marie-Tooth disease type 4C". Int. J. Mol. Med. 11 (1): 45–7. doi:10.3892/ijmm.11.1.45. PMID 12469216.
- Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg EA, Mayer TU, Barr FA (2003). "Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis". J. Cell Biol. 162 (5): 863–75. doi:10.1083/jcb.200306009. PMC 2172827. PMID 12939256.
- Gruneberg U, Neef R, Honda R, Nigg EA, Barr FA (2004). "Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2". J. Cell Biol. 166 (2): 167–72. doi:10.1083/jcb.200403084. PMC 2172317. PMID 15263015.
- Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Taniuchi K, Nakagawa H, Nakamura T, Eguchi H, Ohigashi H, Ishikawa O, Katagiri T, Nakamura Y (2005). "Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell". Cancer Res. 65 (1): 105–12. PMID 15665285.
- Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
- Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
- Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
External links
- KIF20A human gene location in the UCSC Genome Browser.
- KIF20A human gene details in the UCSC Genome Browser.
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