KDM1B

KDM1B
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
Aliases KDM1B, AOF1, C6orf193, LSD2, bA204B7.3, dJ298J15.2, lysine demethylase 1B
External IDs HomoloGene: 131158 GeneCards: KDM1B
Orthologs
Species Human Mouse
Entrez

221656

n/a

Ensembl

ENSG00000165097

n/a

UniProt

Q8NB78

n/a

RefSeq (mRNA)

NM_153042

n/a

RefSeq (protein)

NP_694587.3

n/a

Location (UCSC) Chr 6: 18.16 – 18.22 Mb n/a
PubMed search [1] n/a
Wikidata
View/Edit Human

Lysine (K)-specific demethylase 1B is a protein that in humans is encoded by the KDM1B gene.[2]

Function

Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function.[2][3]

References

  1. "Human PubMed Reference:".
  2. 1 2 "Entrez Gene: Lysine (K)-specific demethylase 1B".
  3. Karytinos A, Forneris F, Profumo A, Ciossani G, Battaglioli E, Binda C, Mattevi A (Jun 2009). "A novel mammalian flavin-dependent histone demethylase". The Journal of Biological Chemistry. 284 (26): 17775–82. doi:10.1074/jbc.M109.003087. PMC 2719416Freely accessible. PMID 19407342.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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