Isoeugenol synthase

Isoeugenol synthase (EC 1.1.1.319, IGS1, t-anol/isoeugenol synthase 1) is an enzyme with systematic name eugenol:NADP⁺ oxidoreductase (coniferyl acetate reducing).^[1]^[2]^[3] This enzyme catalyses the following chemical reaction.^[4]

\rightleftharpoons

coniferyl acetate + NADPH + H⁺

The enzyme acts in the reverse direction.

References

↑ Koeduka, T.; Fridman, E.; Gang, D.R.; Vassão, D.G.; Jackson, B.L.; Kish, C.M.; Orlova, I.; Spassova, S.M.; Lewis, N.G.; Noel, J.P.; Baiga, T.J.; Dudareva, N.; Pichersky, E. (2006). "Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester". Proc. Natl. Acad. Sci. USA. 103: 10128–10133. doi:10.1073/pnas.0603732103. PMC 1502517. PMID 16782809.
↑ Koeduka, T.; Louie, G.V.; Orlova, I.; Kish, C.M.; Ibdah, M.; Wilkerson, C.G.; Bowman, M.E.; Baiga, T.J.; Noel, J.P.; Dudareva, N.; Pichersky, E. (2008). "The multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages". Plant J. 54: 362–374. doi:10.1111/j.1365-313X.2008.03412.x. PMC 2741023. PMID 18208524.
↑ Koeduka, T.; Baiga, T.J.; Noel, J.P.; Pichersky, E. (2009). "Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C₇-C₈ propenyl side chain". Plant Physiol. 149: 384–394. doi:10.1104/pp.108.128066. PMC 2613694. PMID 18987218.
↑ Gupta A. K.; Schauvinhold I.; Pichersky E.; Schiestl F. P. (2014). "Eugenol synthase genes in floral scent variation in Gymnadenia species". Functional & Integrative Genomics. doi:10.1007/s10142-014-0397-9.

Isoeugenol synthase at the US National Library of Medicine Medical Subject Headings (MeSH)

Oxidoreductases: alcohol oxidoreductases (EC 1.1)

1.1.1: NAD/NADP acceptor	3-hydroxyacyl-CoA dehydrogenase 3-hydroxybutyryl-CoA dehydrogenase Alcohol dehydrogenase Aldo-keto reductase 1A1 1B1 1B10 1C1 1C3 1C4 7A2 Aldose reductase Beta-Ketoacyl ACP reductase Carbohydrate dehydrogenases Carnitine dehydrogenase D-malate dehydrogenase (decarboxylating) DXP reductoisomerase Glucose-6-phosphate dehydrogenase Glycerol-3-phosphate dehydrogenase HMG-CoA reductase IMP dehydrogenase Isocitrate dehydrogenase Lactate dehydrogenase L-threonine dehydrogenase L-xylulose reductase Malate dehydrogenase Malate dehydrogenase (decarboxylating) Malate dehydrogenase (NADP+) Malate dehydrogenase (oxaloacetate-decarboxylating) Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) Phosphogluconate dehydrogenase Sorbitol dehydrogenase Hydroxysteroid dehydrogenase: 3 Beta 3-beta-HSD NSDHL 11 Beta HSD11B1 HSD11B2 17 Beta

1.1.2: cytochrome acceptor	D-lactate dehydrogenase (cytochrome) D-lactate dehydrogenase (cytochrome c-553) Mannitol dehydrogenase (cytochrome)

1.1.3: oxygen acceptor	Glucose oxidase L-gulonolactone oxidase Xanthine oxidase

1.1.4: disulfide as acceptor	Vitamin K epoxide reductase Vitamin-K-epoxide reductase (warfarin-insensitive)

1.1.5: quinone/similar acceptor	Malate dehydrogenase (quinone) Quinoprotein glucose dehydrogenase

1.1.99: other acceptors	Choline dehydrogenase L2HGDH

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

This article is issued from Wikipedia - version of the 5/21/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.