Interstate 280

Interstate 280 may refer to:

Interstate 280 (California), a north–south freeway running from San Jose to San Francisco
Interstate 280 (Illinois–Iowa), part of the beltway around the Quad Cities
Interstate 280 (New Jersey), a connector from Interstate 80 to Interstate 95 in Newark
Interstate 280 (Ohio), a connector in Toledo from Interstate 80 to Interstate 75
Interstate 276, once designated as I-280 when I-76 was I-80S
Interstate 680 (Iowa–Nebraska), once designated as I-280

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