ISC

ISC may refer to:

Art and fiction

Imperial Space Command, a fictional organization in the books by Catherine Asaro
Indian Society of Cinematographers, a non-profit cultural and educational organisation
In Strict Confidence, a German electro-industrial band
Intervision Song Contest, an Eastern Bloc version of the Eurovision Song Contest from the 1970s and 1980s

Initiative for Software Choice, a group of software vendors
Interactive Systems Corporation, a (defunct) Unix vendor
Internet Storm Center, a program run by the SANS Institute that monitors the level of malicious activity on the internet
International Supercomputing Conference, a yearly conference on Supercomputing which has been held in Europe
Internet Systems Consortium, an organization that develops Internet software
- ISC license, a free software license introduced by the Internet Systems Consortium

Independent Schools Council, a British organization representing independent schools
Indian School Certificate, an examination conducted by the Council for the Indian School Certificate Examinations
Institut supérieur du commerce de Paris, a French business school
International School of Curitiba a school in Curitiba, Brazil
International School of Choueifat
International Students’ Committee, an independent non-profit organisation and accredited association of the University of St. Gallen
International Student Conference, a nonpartisan rival organization to the International Union of Students
International Studies Conference, annual conference in Łódź, Poland, for Polish secondary school students who aim to study abroad

Induced stem cells
International Commission on Stratigraphy, aka International Stratigraphy Committee, the "working committee" of the International Union of Geological Sciences
International Seismological Centre, a seismology data center
Islamic World Science Citation Database (ISC), Iranian regional citation index

International Shooto Commission, an international commission of combat sports called MMA
International Softball Congress, a North American softball tournament organization
International Speedway Corporation, the owner of numerous American NASCAR racetracks
International Sports Clothing, an Australian sports apparel manufacturer
International Sportsworld Communicators, the owner of the commercial rights to the World Rally Championship
Indonesia Soccer Championship, a football league system in Indonesia

Infiltration Surveillance Center, the (defunct) command center for Operation Igloo White in Nakhon Phanom, Thailand
Intelligence and Security Committee, a committee of the UK Parliament
International Signal and Control, an American defense contractor
International Socialist Commission
Internet Scrabble Club, an online Scrabble website
St Mary's Airport (Isles of Scilly), an airport in the Isles of Scilly with the IATA airport code ISC
International service center, a type of USPS facility