IFT81
Intraflagellar transport protein 81 homolog is a protein that in humans is encoded by the IFT81 gene.[3][4] Together with IFT74/72 it forms a core complex to build IFT particles[5] which are required for cilium formation. Additionally, it interacts with basal body components as CEP170[6] which regulates the disassembly of the cilium.
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ "Entrez Gene: intraflagellar transport 81 homolog (Chlamydomonas)".
- ↑ Higashi M, Kobayashi K, Iijima M, Wakana S, Horiuchi M, Yasuda T, Yoshida G, Kanmura Y, Saheki T (December 2000). "Genomic organization and mapping of mouse CDV (carnitine deficiency-associated gene expressed in ventricle)-1 and its related CDV-1R gene". Mamm. Genome. 11 (12): 1053–7. doi:10.1007/s003350010207. PMID 11130971.
- ↑ Lucker BF, Behal RH, Qin H, Siron LC, Taggart WD, Rosenbaum JL, Cole DG (July 2005). "Characterization of the intraflagellar transport complex B core: direct interaction of the IFT81 and IFT74/72 subunits". J. Biol. Chem. 280 (30): 27688–96. doi:10.1074/jbc.M505062200. PMID 15955805.
- ↑ Lamla, Stefan (2009). Functional characterisation of the centrosomal protein Cep170 (Thesis). LMU München: Faculty of Biology.
Further reading
- Melzer D, Perry JR, Hernandez D, et al. (2008). Cheung VG, ed. "A genome-wide association study identifies protein quantitative trait loci (pQTLs).". PLoS Genet. 4 (5): e1000072. doi:10.1371/journal.pgen.1000072. PMC 2362067
. PMID 18464913. 
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Peng J, Yu L, Horiuchi M, et al. (2002). "Identification of human CDV-1R and mouse Cdv-1R, two novel proteins with putative signal peptides, especially highly expressed in testis and increased with the male sex maturation". Mol. Biol. Rep. 29 (4): 353–62. doi:10.1023/A:1021232518628. PMID 12549821.
- Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.