Diamine oxidase
| Diamine oxidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifiers | |||||||||
| EC number | 1.4.3.22 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
| |||||||||
Diamine oxidase, also known as histaminase, is an enzyme (EC 1.4.3.22) involved in the metabolism, oxidation, and inactivation of histamine in animals. Highest content is observed in the digestive tract and placenta. It is also secreted by eosinophils.[3][4]
References
- ↑ PDB: 3HI7
- ↑ McGrath AP, Hilmer KM, Collyer CA, Shepard EM, Elmore BO, Brown DE, Dooley DM, Guss JM (2009). "Structure and inhibition of human diamine oxidase". Biochemistry. 48 (41): 9810–22. doi:10.1021/bi9014192. PMC 2791411
. PMID 19764817. - ↑ Zeiger RS, Colten HR (1977). "Histaminase release from human eosinophils". Journal of Immunology. 118 (2): 540–3. PMID 402420.
- ↑ Agúndez JA, Ayuso P, Cornejo-García JA, Blanca M, Torres MJ, Doña I, Salas M, Blanca-López N, Canto G, Rondon C, Campo P, Laguna JJ, Fernández J, Martínez C, García-Martín E (2012). "The diamine oxidase gene is associated with hypersensitivity response to non-steroidal anti-inflammatory drugs". PLoS ONE. 7 (11): e47571. doi:10.1371/journal.pone.0047571. PMC 3495953. PMID 23152756.
External links
- Amine Oxidase (Copper-Containing) at the US National Library of Medicine Medical Subject Headings (MeSH)
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