Hemodialysis product

Hemodialysis product (HDP) - is a number used to quantify hemodialysis and peritoneal dialysis treatment adequacy.

It was proposed by Scribner and Oreopoulous because of their perceived inadequacy of the Kt/V measure of dialysis adequacy.

The HDP is defined by the following empirical formula:

HDP = t * f ²

Where:

HDP - hemodialysis product
t - dialysis time (hours/dialysis session)
f - dialysis frequency (dialysis sessions/week)

The formula, like all empirical formulae, has no theoretical basis. The HDP has not seen widespread use. An Egyptian study published in 2011 found that HDP is "a valid test with high sensitivity and specificity for assessment of adequacy of hemodialysis in comparison to KT/V and URR." The formula has been tested by me using nxstage system one 4.78 x 7 x 7 = 234 During dialysis I performed potassium blood electrolyte test. Using 2K dialysate potassium level went to normal. Here is the reason: lactate 45 instead of bicarbonate. This is the theoretical basis ,Scribner has no machine that uses lactate but peritoneal is using lactate. Also with HDP 234 my BP is normal without medications. My hemoglobin is 14.7 no EPO.

References

^ Scribner BH, Oreopoulos DG, The Hemodialysis Product (HDP): A Better Index of Dialysis Adequacy than Kt/V, Dialysis & Transplantation, 2002 Jan;31(1):13-15. Full Text Full Text (Mirror)
^ Eltayeb M, Elshinawy H, Ramadan A, Abouellal H, Hemodialysis Product: A Reliable New Index for Dialysis Adequacy, Sci. Med. J., Jan. 2011; 23 (1): 73-93, ISSN 1110-5607. Full text

Physiology of the kidneys and acid-base physiology

Renal function

Secretion	clearance Pharmacokinetics Clearance of medications Urine flow rate

Reabsorption	Solvent drag sodium chloride urea glucose oligopeptides protein

Renal function	Glomerular filtration rate Creatinine clearance Renal clearance ratio Urea reduction ratio Kt/V Standardized Kt/V Measures of dialysis Hemodialysis product PAH clearance (Effective renal plasma flow Extraction ratio)

Filtration	Renal blood flow Ultrafiltration Countercurrent exchange Filtration fraction

Hormones

Acid-base balance

Body water: Intracellular fluid/Cytosol

Buffering

Other

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