HMG20B

HMG20B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases HMG20B, BRAF25, BRAF35, HMGX2, HMGXB2, PP7706, SMARCE1r, SOXL, pp8857, high mobility group 20B
External IDs MGI: 1341190 HomoloGene: 74949 GeneCards: HMG20B
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

10362

15353

Ensembl

ENSG00000064961

ENSMUSG00000020232

UniProt

Q9P0W2

Q9Z104

RefSeq (mRNA)

NM_006339

NM_001163165
NM_001163166
NM_010440

RefSeq (protein)

NP_006330.2

NP_001156637.1
NP_001156638.1
NP_034570.1

Location (UCSC) Chr 19: 3.57 – 3.58 Mb Chr 10: 81.35 – 81.35 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related is a protein that in humans is encoded by the HMG20B gene.[3][4]


Interactions

HMG20B has been shown to interact with:

References

  1. ↑ "Human PubMed Reference:".
  2. ↑ "Mouse PubMed Reference:".
  3. ↑ Sumoy L, Carim L, Escarceller M, Nadal M, Gratacòs M, Pujana MA, Estivill X, Peral B (Jun 2000). "HMG20A and HMG20B map to human chromosomes 15q24 and 19p13.3 and constitute a distinct class of HMG-box genes with ubiquitous expression". Cytogenetics and Cell Genetics. 88 (1-2): 62–7. doi:10.1159/000015486. PMID 10773667.
  4. ↑ "Entrez Gene: HMG20B high-mobility group 20B".
  5. 1 2 3 4 5 Hakimi MA, Bochar DA, Chenoweth J, Lane WS, Mandel G, Shiekhattar R (May 2002). "A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes". Proceedings of the National Academy of Sciences of the United States of America. 99 (11): 7420–5. doi:10.1073/pnas.112008599. PMC 124246Freely accessible. PMID 12032298.
  6. ↑ Marmorstein LY, Kinev AV, Chan GK, Bochar DA, Beniya H, Epstein JA, Yen TJ, Shiekhattar R (January 2001). "A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression". Cell. 104 (2): 247–57. doi:10.1016/S0092-8674(01)00209-4. PMID 11207365.
  7. ↑ Hakimi MA, Dong Y, Lane WS, Speicher DW, Shiekhattar R (February 2003). "A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes". The Journal of Biological Chemistry. 278 (9): 7234–9. doi:10.1074/jbc.M208992200. PMID 12493763.
  8. ↑ Lee YM, Kim W (September 2003). "Association of human kinesin superfamily protein member 4 with BRCA2-associated factor 35". The Biochemical Journal. 374 (Pt 2): 497–503. doi:10.1042/BJ20030452. PMC 1223617Freely accessible. PMID 12809554.
  9. ↑ Iwase S, Januma A, Miyamoto K, Shono N, Honda A, Yanagisawa J, Baba T (September 2004). "Characterization of BHC80 in BRAF-HDAC complex, involved in neuron-specific gene repression". Biochemical and Biophysical Research Communications. 322 (2): 601–8. doi:10.1016/j.bbrc.2004.07.163. PMID 15325272.

Further reading

  • Wattler F, Wattler S, Kelly M, Skinner HB, Nehls M (September 1999). "Cloning, chromosomal location, and expression analysis of murine Smarce1-related, a new member of the high-mobility 365 group gene family". Genomics. 60 (2): 172–8. doi:10.1006/geno.1999.5913. PMID 10486208. 
  • Marmorstein LY, Kinev AV, Chan GK, Bochar DA, Beniya H, Epstein JA, Yen TJ, Shiekhattar R (January 2001). "A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression". Cell. 104 (2): 247–57. doi:10.1016/S0092-8674(01)00209-4. PMID 11207365. 
  • Lee YM, Shin H, Choi W, Ahn S, Kim W (April 2002). "Characterization of human SMARCE1r high-mobility-group protein". Biochimica et Biophysica Acta. 1574 (3): 269–76. doi:10.1016/s0167-4781(01)00373-6. PMID 11997092. 
  • Hakimi MA, Bochar DA, Chenoweth J, Lane WS, Mandel G, Shiekhattar R (May 2002). "A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes". Proceedings of the National Academy of Sciences of the United States of America. 99 (11): 7420–5. doi:10.1073/pnas.112008599. PMC 124246Freely accessible. PMID 12032298. 
  • Wang C, McCarty IM, Balazs L, Li Y, Steiner MS (July 2002). "Cloning a cDNA encoding an alternatively spliced protein of BRCA2-associated factor 35". Biochemical and Biophysical Research Communications. 295 (1): 129–35. doi:10.1016/S0006-291X(02)00624-1. PMID 12083779. 
  • Wang C, McCarty IM, Balazs L, Li Y, Steiner MS (July 2002). "Immunohistological detection of BRAF25 in human prostate tumor and cancer specimens". Biochemical and Biophysical Research Communications. 295 (1): 136–41. doi:10.1016/S0006-291X(02)00625-3. PMID 12083780. 
  • Hakimi MA, Dong Y, Lane WS, Speicher DW, Shiekhattar R (February 2003). "A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes". The Journal of Biological Chemistry. 278 (9): 7234–9. doi:10.1074/jbc.M208992200. PMID 12493763. 
  • Lee YM, Kim W (September 2003). "Association of human kinesin superfamily protein member 4 with BRCA2-associated factor 35". The Biochemical Journal. 374 (Pt 2): 497–503. doi:10.1042/BJ20030452. PMC 1223617Freely accessible. PMID 12809554. 
  • Iwase S, Januma A, Miyamoto K, Shono N, Honda A, Yanagisawa J, Baba T (September 2004). "Characterization of BHC80 in BRAF-HDAC complex, involved in neuron-specific gene repression". Biochemical and Biophysical Research Communications. 322 (2): 601–8. doi:10.1016/j.bbrc.2004.07.163. PMID 15325272. 
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 

External links


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