H2AFJ

H2AFJ
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases H2AFJ, H2AJ, H2A histone family member J
External IDs MGI: 3606192 HomoloGene: 128575 GeneCards: H2AFJ
Orthologs
Species Human Mouse
Entrez

55766

232440

Ensembl

ENSG00000246705

ENSMUSG00000060032

UniProt

Q9BTM1

Q8R1M2

RefSeq (mRNA)

NM_018267
NM_177925

NM_177688

RefSeq (protein)

NP_808760.1

NP_808356.1

Location (UCSC) Chr 12: 14.77 – 14.78 Mb Chr 6: 136.81 – 136.81 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Histone H2A.J is a protein that in humans is encoded by the H2AFJ gene.[3]

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is located on chromosome 12 and encodes a variant H2A histone. The protein is divergent at the C-terminus compared to the consensus H2A histone family member.[3]

References

Further reading


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