Fungating lesion

A fungating lesion is a skin lesion that fungates, that is, becomes like a fungus in its appearance or growth rate. It is marked by ulcerations (breaks on the skin or surface of an organ) and necrosis (death of living tissue) and usually presents a foul odor. This kind of lesion may occur in many types of cancer, including breast cancer, melanoma, and squamous cell carcinoma, and especially in advanced disease. The characteristic malodorous smell is caused by dimethyl trisulfide.[1] It is usually not literally a fungal infection but rather a neoplastic growth with necrosing portions.

References

  1. ↑ Shirasu, Mika; Nagai, Shunji; Hayashi, Ryuichi; Ochiai, Atsushi; Touhara, Kazushige (2009). "Dimethyl trisulfide as a characteristic odor associated with fungating cancer wounds". Bioscience, Biotechnology, and Biochemistry. 73 (9): 2117–20. doi:10.1271/bbb.90229. PMID 19734656.

External links

 This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".


This article is issued from Wikipedia - version of the 11/10/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.