Ectomesenchymal chondromyxoid tumor

Ectomesenchymal chondromyxoid tumor (ECT) is a benign intraoral tumor with presumed origin from undifferentiated (ecto)mesenchymal cells.[1] There are some who think it is a myoepithelial tumor type.[2]

Controversies about origin

Signs and Symptoms

Patients present with a painless, slow-growing mass usually within the tongue (most commonly the anterior dorsal tongue). There is an intact surface epithelium.[1][5][6]

Management

Pathology findings

Macroscopic

Microscopic Pathology

Immunohistochemistry

Ancillary Studies

Differential diagnoses

The tumor is quite unique, but other tumors are considered in the differential diagnosis histologically. They included pleomorphic adenoma, myoepithelioma, myxoid neurofibroma, neurothekeoma (nerve sheath myxoma), chondroid choristoma, extraskeletal myxoid chondrosarcoma, focal oral mucinosis, and an ossifying fibromyxoid tumor of soft parts.[1]

Epidemiology

Exceedingly rare, this tumor develops in a wide age range, although often in young patients without a sex predilection. The vast majority develop within the anterior dorsal tongue,[1] with palate and base of tongue rarely affected.[8]

References

  1. 1 2 3 4 5 6 7 8 9 10 Smith BC, Ellis GL, Meis-Kindblom JM, Williams SB (May 1995). "Ectomesenchymal chondromyxoid tumor of the anterior tongue. Nineteen cases of a new clinicopathologic entity". Am J Surg Pathol. 19: 519–30. doi:10.1097/00000478-199505000-00003. PMID 7726361.
  2. Woo VL, Angiero F, Fantasia JE (May 2005). "Myoepithelioma of the tongue". Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 99: 581–9. doi:10.1016/j.tripleo.2004.12.016. PMID 15829881.
  3. 1 2 Goveas N, Ethunandan M, Cowlishaw D, Flood TR (November 2006). "Ectomesenchymal chondromyxoid tumour of the tongue: Unlikely to originate from myoepithelial cells". Oral Oncol. 42: 1026–8. doi:10.1016/j.oraloncology.2006.06.004. PMID 17011812.
  4. Seo SH, Shin DH, Kang HJ, Choi KU, Kim JY, Park do Y, Lee CH, Sol MY, Lee JC (October 2010). "Reticulated myxoid tumor of the tongue: 2 cases supporting an expanded clinical and immunophenotypic spectrum of ectomesenchymal chondromyxoid tumor of the tongue". Am J Dermatopathol. 32: 660–4. doi:10.1097/DAD.0b013e3181d7d3bf. PMID 20661118.
  5. 1 2 3 4 5 Kannan R, Damm DD, White DK, Marsh W, Allen CM (October 1996). "Ectomesenchymal chondromyxoid tumor of the anterior tongue: a report of three cases". Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 82: 417–22. PMID 8899780.
  6. 1 2 3 4 5 Pires FR, Abrahão AC, Cabral MG, Azevedo RS, Horta MC, Martins CR, de Almeida OP, Chen SY (December 2009). "Clinical, histological and immunohistochemical features of ectomesenchymal chondromyxoid tumor". Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 108: 914–9. doi:10.1016/j.tripleo.2009.07.007. PMID 19800267.
  7. 1 2 3 Angiero F (November 2010). "Ectomesenchymal chondromyxoid tumour of the tongue. A review of histological and immunohistochemical features". Anticancer Res. 30: 4685–9. PMID 21115924.
  8. Nigam S, Dhingra KK, Gulati A (February 2006). "Ectomesenchymal chondromyxoid tumor of the hard palate--a case report". J Oral Pathol Med. 35: 126–8. doi:10.1111/j.1600-0714.2006.00368.x. PMID 16430745.

Further reading

This article is issued from Wikipedia - version of the 11/25/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.