EPS8L3

EPS8L3

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1WXT

Identifiers

EPS8L3, EPS8R3, EPS8 like 3

External IDs

MGI: 2139743 HomoloGene: 15878 GeneCards: EPS8L3

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


79574


99662


ENSG00000198758


ENSMUSG00000040600


Q8TE67


Q91WL0

RefSeq (mRNA)


NM_024526 NM_133181 NM_139053 NM_001319952


NM_133867

RefSeq (protein)


NP_078802.2 NP_573444.2 NP_620641.1 NP_001306881.1


NP_598628.1

Location (UCSC)

Chr 1: 109.75 – 109.76 Mb

Chr 3: 107.88 – 107.89 Mb

PubMed search

^[1]

^[2]

View/Edit Human

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Epidermal growth factor receptor kinase substrate 8-like protein 3 is an enzyme that in humans is encoded by the EPS8L3 gene.^[3]^[4]

This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist.^[4]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Tocchetti A, Confalonieri S, Scita G, Di Fiore PP, Betsholtz C (Mar 2003). "In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure". Genomics. 81 (2): 234–44. doi:10.1016/S0888-7543(03)00002-8. PMID 12620401.
1 2 "Entrez Gene: EPS8L3 EPS8-like 3".

Further reading

Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Offenhäuser N, Borgonovo A, Disanza A, et al. (2004). "The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway.". Mol. Biol. Cell. 15 (1): 91–8. doi:10.1091/mbc.E03-06-0427. PMC 307530. PMID 14565974.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

PDB gallery

1wxt: Solution structure of the SH3 domain of human hypothetical protein FLJ21522

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