ELL (gene)

ELL
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases ELL, C19orf17, ELL1, MEN, PPP1R68, elongation factor for RNA polymerase II
External IDs MGI: 109377 HomoloGene: 4762 GeneCards: ELL
RNA expression pattern




More reference expression data
Orthologs
Species Human Mouse
Entrez

8178

13716

Ensembl

ENSG00000105656

ENSMUSG00000070002

UniProt

P55199

O08856

RefSeq (mRNA)

NM_006532

NM_007924

RefSeq (protein)

NP_006523.1

NP_031950.2

Location (UCSC) Chr 19: 18.44 – 18.52 Mb Chr 8: 70.54 – 70.59 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

RNA polymerase II elongation factor ELL is an enzyme that in humans is encoded by the ELL gene.[3][4][5]

Interactions

ELL (gene) has been shown to interact with P53.[6]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Thirman MJ, Levitan DA, Kobayashi H, Simon MC, Rowley JD (Jan 1995). "Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia". Proc Natl Acad Sci U S A. 91 (25): 12110–4. doi:10.1073/pnas.91.25.12110. PMC 45386Freely accessible. PMID 7991593.
  4. Shilatifard A, Lane WS, Jackson KW, Conaway RC, Conaway JW (Apr 1996). "An RNA polymerase II elongation factor encoded by the human ELL gene". Science. 271 (5257): 1873–6. doi:10.1126/science.271.5257.1873. PMID 8596958.
  5. "Entrez Gene: ELL elongation factor RNA polymerase II".
  6. Shinobu N, Maeda T, Aso T, Ito T, Kondo T, Koike K, Hatakeyama M (Jun 1999). "Physical interaction and functional antagonism between the RNA polymerase II elongation factor ELL and p53". J. Biol. Chem. 274 (24): 17003–10. doi:10.1074/jbc.274.24.17003. PMID 10358050.

Further reading


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