Inorganic diphosphatase

inorganic diphosphatase

Pyrophosphatase (inorganic) hexamer, E.Coli
Identifiers
EC number 3.6.1.1
CAS number 9024-82-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an inorganic diphosphatase (EC 3.6.1.1) is an enzyme that catalyzes the chemical reaction

diphosphate + H2O 2 phosphate

Thus, the two substrates of this enzyme are diphosphate and H2O, whereas its product is phosphate.[1]

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is diphosphate phosphohydrolase. This enzyme participates in oxidative phosphorylation. It employs one cofactor, metal.

References

  1. Rafter GW (1960). "Pyrophosphate metabolism in liver mitochondria". J. Biol. Chem. 235: 24752477.

Further reading

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