Debbie C. Crans
| Debbie C. Crans | |
|---|---|
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| Born | August 13, 1955[1] |
| Website |
www |
| Academic background | |
| Doctoral advisor | George M. Whitesides |
| Academic work | |
| Institutions |
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Debbie C. Crans is a professor of chemistry at Colorado State University,[2] specializing in "fundamental chemistry and biochemistry of drugs with particular interest in vanadium and other transition metal ions as metals in medicine and their mechanisms of toxicity".[1]
Education
Debbie Crans studied at the University of Copenhagen, studying for her Cand. Scient. 1. part (BS) in 1974-1978, then her Cand. Scient. 2. part (research) in 1978-1980. She then moved to Harvard University in the US to work under George M. Whitesides, and she successfully defended her PhD dissertation on "Methodology in Enzyme-Catalyzed Organic Synthesis: Glycerol Kinase Catalyzed Phosphorylations". She went on to do postdoctoral work with Orville L. Chapman and Paul D. Boyer at the University of California, Los Angeles from 1985–1986, studying "Mechanistic Enzymology on F1-ATP Synthase from Chloroplasts and Beef Heart".[1]
Career and awards
Dr. Crans is best known for her work on the role of vanadium in biological systems, especially the effects of its compounds on diabetes. She has worked as senior editor several books on vanadium, such as Vanadium Compounds: Chemistry, Biochemistry, and Therapeutic Applications,[3] Vanadium: The Versatile Metal[4] and Vanadium in Biochemistry.[5] Her study on "Effects of vanadium complexes with organic ligands on glucose metabolism: a comparison study in diabetic rats"[6] describes the use of vanadium compounds as hypoglycemic agents, and it has been widely cited.[7]
In 2015, Dr. Crans received the Arthur C. Cope Scholar Award "for her characterization of the structures and properties of organic vanadium complexes and applying these principles to understand the impact of different coordinated ligands on anti-diabetic activity". In 2015 she was also made Professor Laureate at Colorado State.[1]
References
- 1 2 3 4 Crans, Debbie C. "Crans Brief Resume". Retrieved 24 August 2016.
- ↑ "Debbie Crans". Colorado State University. Retrieved 24 August 2016.
- ↑ Tracy, Alan S.; Crans, Debbie C., eds. (1998). Vanadium Compounds: Chemistry, Biochemistry, and Therapeutic Applications. ACS Symposium Series. Washington, DC: American Chemical Society.
- ↑ Kustin, Kenneth; Pessoa, João Costa; Crans, Debbie C., eds. (2007). Vanadium: The Versatile Metal. ACS Symposium Series. Washington, DC: American Chemical Society.
- ↑ Crans, Debbie C.; Simone, Carmen (2013). Vanadium in Biochemistry. Hoboken, NJ: Wiley.
- ↑ Crans, Debbie C. (30 May 2000). "Chemistry and insulin-like properties of vanadium(IV) and vanadium(V) compounds". Journal of Inorganic Biochemistry. Elsevier. 80 (1-2): 123–131.
- ↑ "Chemistry and insulin-like properties of vanadium (IV) and vanadium (V) compounds". Google Scholar. Retrieved 24 August 2016.