DYNLT1

DYNLT1
Identifiers
Aliases DYNLT1, CW-1, TCTEL1, tctex-1, dynein light chain Tctex-type 1
External IDs MGI: 98643 HomoloGene: 4754 GeneCards: DYNLT1
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

6993

21648

Ensembl

ENSG00000146425

ENSMUSG00000096255

UniProt

P63172

P51807

RefSeq (mRNA)

NM_006519
NM_001291602
NM_001291603

NM_009342

RefSeq (protein)

NP_006510.1

NP_001160099.1
NP_001160101.1
NP_001160102.1
NP_033368.1

Location (UCSC) Chr 6: 158.64 – 158.64 Mb Chr 17: 6.43 – 6.44 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Dynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene.[3][4][5]

Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. TCTEX1 is a dynein light chain involved in cargo binding (Chuang et al., 2005).[supplied by OMIM][5]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Watanabe TK, Fujiwara T, Shimizu F, Okuno S, Suzuki M, Takahashi E, Nakamura Y, Hirai Y (Jul 1996). "Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1, to 6q". Cytogenet Cell Genet. 73 (1-2): 153–6. doi:10.1159/000134329. PMID 8646886.
  4. Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005). "Cytoplasmic dynein nomenclature". J Cell Biol. 171 (3): 411–3. doi:10.1083/jcb.200508078. PMC 2171247Freely accessible. PMID 16260502.
  5. 1 2 "Entrez Gene: DYNLT1 dynein, light chain, Tctex-type 1".

Further reading


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