Omphalotus subilludens
| Omphalotus subilludens | |
|---|---|
| Scientific classification | |
| Kingdom: | Fungi |
| Division: | Basidiomycota |
| Class: | Agaricomycetes |
| Order: | Agaricales |
| Family: | Marasmiaceae |
| Genus: | Omphalotus |
| Species: | O. subilludens |
| Binomial name | |
| Omphalotus subilludens (Murrill) H.E. Bigelow 1982 | |
| Synonyms | |
|
Clitocybe subilludens (Murrill) Murrill 1945[1]
| |
Omphalotus subilludens is a fungus species in the genus Omphalotus. The type collection was found by Murrill on July 26, 1944 in Gainesville, Florida. It has also been recorded from Texas.
Atromentin and thelephoric acid are chemical compounds found in cultures of C. subilludens.[2] Atromentin is an effective anticoagulant, and similar in biological activity to the well-known anticoagulant heparin.[3] Atromentin also possesses antibacterial activity, inhibiting the enzyme enoyl-acyl carrier protein reductase (essential for the biosynthesis of fatty acids) in the bacteria Streptococcus pneumoniae.[4]
It also produces illudoids.[5]
References
- ↑ Murrill, W.A., 1945, Quarterly Journal of the Florida Academy of Science 8(2): 198
- ↑ Sullivan, G.; Garrett, R. D.; Lenehan, R. F. (1971). "Occurrence of atromentin and thelephoric acid in cultures ofclitocybe subilludens". Journal of Pharmaceutical Sciences. 60 (11): 1727–9. doi:10.1002/jps.2600601134. PMID 4332377.
- ↑ Khanna JM, Malone MH, Euler KL, Brady LR (1965). "Atromentin – anticoagulant from Hydnellum diabolus". Journal of Pharmaceutical Science. 54 (7): 1016–20. doi:10.1002/jps.2600540714. PMID 5862512.
- ↑ Zheng CJ, Sohn MJ, Kim WG (2006). "Atromentin and leucomelone, the first inhibitors specific to enoyl-ACP reductase (FabK) of Streptococcus pneumoniae". Journal of Antibiotics. 59 (12): 808–12. doi:10.1038/ja.2006.108. PMID 17323650.
- ↑ Illudoids from Omphalotus olivascens and Clitocybe subilludens. Nair M. S. R., Carey S. T. and Rogerson C. T., Mycologia, 1983, vol. 75, no5, pages 920-922, INIST:9415717
External links
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