CXCL15

Cxcl15
Identifiers
Aliases chemokine (C-X-C motif) ligand 15Il8Scyb15lungkineweche
External IDs GeneCards:
Orthologs
Species Human Mouse
Entrez

20309

n/a

Ensembl

ENSMUSG00000029375

n/a

UniProt

Q9WVL7

n/a

RefSeq (mRNA)

NM_011339

n/a

RefSeq (protein)

NP_035469.1

n/a

Location (UCSC) n/a n/a
PubMed search [1] n/a
Wikidata
View/Edit Human

Chemokine (C-X-C motif) ligand 15 (CXCL15) is a small cytokine belonging to the CXC chemokine family that has been described in the mouse. This chemokine is also known under the name lungkine. CXCL15 is an ELR+ CXC chemokine (it contains the amino acid sequence E-L-R immediately before its CXC motif) that recruits neutrophils during inflammation of the lungs. It is highly abundant in epithelial cells of the lung,[2] and can also be found in other mucosal organs such as the urogenital and gastrointestinal tracts, and in endocrine organs like the adrenal gland.[3] The gene for CXCL15 is found on mouse chromosome 5.

References

  1. ↑ "Human PubMed Reference:".
  2. ↑ Rossi D, Hurst S, Xu Y, Wang W, Menon S, Coffman R, Zlotnik A (1999). "Lungkine, a novel CXC chemokine, specifically expressed by lung bronchoepithelial cells". J Immunol. 162 (9): 5490–7. PMID 10228029.
  3. ↑ Schmitz J, McCracken V, Dimmitt R, Lorenz R (2007). "Expression of CXCL15 (Lungkine) in Murine Gastrointestinal, Urogenital, and Endocrine Organs". J Histochem Cytochem. 55 (5): 515–24. doi:10.1369/jhc.6A7121.2007. PMID 17242461.



This article is issued from Wikipedia - version of the 6/1/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.