CD300LF

CD300LF
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases CD300LF, CD300f, CLM-1, CLM1, IREM-1, IREM1, IgSF13, LMIR3, NKIR, CD300 molecule like family member f
External IDs MGI: 2442359 HomoloGene: 51396 GeneCards: CD300LF
Orthologs
Species Human Mouse
Entrez

146722

246746

Ensembl

ENSG00000186074

ENSMUSG00000047798

UniProt

Q8TDQ1

Q6SJQ7

RefSeq (mRNA)

NM_001169153
NM_145634

RefSeq (protein)

NP_001162624.1
NP_663609.2

Location (UCSC) Chr 17: 74.69 – 74.71 Mb Chr 11: 115.12 – 115.13 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

CMRF35-like molecule 1 is a protein that in humans is encoded by the CD300LF gene.[3][4]

CD300LF is an inhibitory receptor of the Ig superfamily expressed on myeloid cells. It mediates negative regulatory signals by recruiting SHP1 (PTPN6; MIM 176883) or SHIP (INPP5D; MIM 601582) (Sui et al., 2004; Alvarez-Errico et al., 2004).[supplied by OMIM][4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (Oct 2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697Freely accessible. PMID 12975309.
  4. 1 2 "Entrez Gene: CD300LF CD300 molecule-like family member f".

Further reading


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