Calumenin

CALU
Identifiers
Aliases CALU
External IDs MGI: 1097158 HomoloGene: 936 GeneCards: CALU
RNA expression pattern




More reference expression data
Orthologs
Species Human Mouse
Entrez

813

12321

Ensembl

ENSG00000128595

ENSMUSG00000029767

UniProt

O43852

O35887

RefSeq (mRNA)

NM_001285412
NM_007594
NM_184053

RefSeq (protein)

NP_001124146.1
NP_001186600.1
NP_001186601.1
NP_001186602.1
NP_001210.1

NP_031620.1

Location (UCSC) Chr 7: 128.74 – 128.77 Mb Chr 6: 29.35 – 29.38 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Calumenin is a protein that in humans is encoded by the CALU gene.[3][4]

Calumenin (CALU) is a calcium-binding protein localized in the endoplasmic reticulum (ER) and is involved in such ER functions as protein folding and sorting. Calumenin is a member of the EF-hand superfamily in the ER and Golgi apparatus named CERC. CERC is an acronym for its family members Cab-45, reticulocalbin, Erc-55 (RCN2), and calumenin. The CALU gene encodes a deduced 315-amino acid protein containing 6 EF-hand motifs, 1 potential N-glycosylation site, and a C-terminal ER retention signal. The human and mouse CALU proteins are 98% identical. CALU mRNA is ubiquitously expressed in human tissues and maps to 7q32.[4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Yabe D, Taniwaki M, Nakamura T, Kanazawa N, Tashiro K, Honjo T (Aug 1998). "Human calumenin gene (CALU): cDNA isolation and chromosomal mapping to 7q32". Genomics. 49 (2): 331–3. doi:10.1006/geno.1998.5245. PMID 9598325.
  4. 1 2 "Entrez Gene: CALU calumenin".

Further reading


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