Bisphosphoglycerate phosphatase
bisphosphoglycerate phosphatase | |||||||||
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Identifiers | |||||||||
EC number | 3.1.3.13 | ||||||||
CAS number | 9033-04-9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a bisphosphoglycerate phosphatase (EC 3.1.3.13) is an enzyme that catalyzes the chemical reaction
- 2,3-bisphospho-D-glycerate + H2O 3-phospho-D-glycerate + phosphate
Thus, the two substrates of this enzyme are 2,3-bisphospho-D-glycerate and H2O, whereas its two products are 3-phospho-D-glycerate and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 2,3-bisphospho-D-glycerate 2-phosphohydrolase. Other names in common use include 2,3-diphosphoglycerate phosphatase, diphosphoglycerate phosphatase, 2,3-diphosphoglyceric acid phosphatase, 2,3-bisphosphoglycerate phosphatase, and glycerate-2,3-diphosphate phosphatase. This enzyme participates in glycolysis/gluconeogenesis.
Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1YFK, 1YJX, 2F90, 2H4X, 2H4Z, 2H52, and 2HHJ.
References
- JOYCE BK, GRISOLIA S (1958). "Studies on glycerate 2,3-diphosphatase". J. Biol. Chem. 233 (2): 350–4. PMID 13563500.
- RAPOPORT S, LUEBERING J (1951). "Glycerate-2,3-diphosphatase". J. Biol. Chem. 189 (2): 683–94. PMID 14832286.