Butyrophilin, subfamily 2, member A2

BTN2A2
Identifiers
Aliases BTN2A2, BT2.2, BTF2, BTN2.2, Butyrophilin, subfamily 2, member A2, butyrophilin subfamily 2 member A2
External IDs MGI: 3606486 HomoloGene: 56012 GeneCards: BTN2A2
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

10385

238555

Ensembl

ENSG00000124508

ENSMUSG00000053216

UniProt

Q8WVV5

A4QPC6

RefSeq (mRNA)

NM_001289614
NM_001289615
NM_175938

RefSeq (protein)

NP_001276544.1
NP_787952.2

Location (UCSC) Chr 6: 26.38 – 26.39 Mb Chr 13: 23.48 – 23.49 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Butyrophilin subfamily 2 member A2 is a protein that in humans is encoded by the BTN2A2 gene.[3][4][5]

Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type 1 receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.[5]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Henry J, Miller MM, Pontarotti P (Jul 1999). "Structure and evolution of the extended B7 family". Immunol Today. 20 (6): 285–8. doi:10.1016/S0167-5699(98)01418-2. PMID 10354554.
  4. Ruddy DA, Kronmal GS, Lee VK, Mintier GA, Quintana L, Domingo R Jr, Meyer NC, Irrinki A, McClelland EE, Fullan A, Mapa FA, Moore T, Thomas W, Loeb DB, Harmon C, Tsuchihashi Z, Wolff RK, Schatzman RC, Feder JN (Aug 1997). "A 1.1-Mb transcript map of the hereditary hemochromatosis locus". Genome Res. 7 (5): 441–56. doi:10.1101/gr.7.5.441. PMID 9149941.
  5. 1 2 "Entrez Gene: BTN2A2 butyrophilin, subfamily 2, member A2".

Further reading

External links


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